Molly Gale Hammell
Co-PI (Core Leadership)
Cold Spring Harbor Laboratory
Dr. Molly Gale Hammell is an Associate Professor in the Simons Center for Quantitative Biology at Cold Spring Harbor Laboratory. Prior to starting her own lab at CSHL, she studied small RNA pathways as a postdoctoral fellow in the lab of Victor Ambros at UMASS Medical School. She received a Ben Barres Early Career Acceleration award from CZI’s Neurodegeneration Challenge Network.
Recent ASAP Preprints & Published Papers
Activation of transposable elements is linked to a region- and cell-type-specific interferon response in Parkinson’s disease
Parkinson’s disease (PD) is a common age-related neurodegenerative disorder involving a neuroinflammatory response, the cause of which remains unclear. Transposable elements (TE) have been linked to inflammatory states, but their potential role in PD has not been explored. Using bulk– and single nuclei RNAseq of postmortem brain tissue from four…
LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development
Long interspersed nuclear element 1 (L1) retrotransposons represent a vast source of divergent genetic information. However, mechanistic analysis of whether and how L1s contribute to human developmental programs is lacking, in part due to the challenges associated with specific profiling and manipulation of human L1 expression. Here we show that…
