Background pattern of a brain with neural connections
Ken Marek

Ken Marek

Lead PI (Core Leadership)

University of California, San Diego

Ken is Distinguished Scientist at the Institute for Neurodegenerative Disorders (IND). He serves as a special scientific advisor to The Michael J. Fox Foundation. He has served in leadership roles in several organizations focused on neurodegenerative disorders and has been the recipient of numerous grants to support his work in Parkinson disease, Alzheimer Disease and Huntington disease. He has been awarded the Robert A. Pritzker Prize for Leadership in Parkinson’s Research. He graduated from Yale University School of Medicine and was trained at the Institute for Neurology, London and Johns Hopkins University in neuroscience and neurology. He was a co-founder of IND and Molecular NeuroImaging, LLC.

Teams

PPMI

Themes

PD Functional Genomics

Tags

Protein aggregates Aggregation Cell biology

Recent ASAP Preprints & Published Papers

Parkinson's Progression Markers Initiative: A Milestone-Based Strategy to Monitor PD Progression

Challenge: Identifying a meaningful progression metric for Parkinson's disease (PD) that reflects heterogeneity remains a challenge. Objective: To assess the frequency and baseline predictors of progression to clinically relevant motor and non-motor PD milestones. Methods: Using data from the Parkinson's Progression Markers Initiative (PPMI) de novo PD cohort, we monitored…

Impact of the dopamine system on long-term cognitive impairment in Parkinson disease: an exploratory study

Background Little is known about the impact of the dopamine system on development of cognitive impairment (CI) in Parkinson disease (PD). Using data from a multi-site, international, prospective cohort study, authors explored the impact of dopamine system-related biomarkers on CI in PD. The study provides preliminary evidence that alterations in…

Team PPMI

Ken Marek

Ken Marek

Lead PI (Core Leadership)
Kalpana Merchant

Kalpana Merchant

Co-PI (Core Leadership)
Brit Mollenhauer

Brit Mollenhauer

Co-PI (Core Leadership)
Kathleen Poston

Kathleen Poston

Co-PI (Core Leadership)
Tatyana Simuni

Tatyana Simuni

Co-PI (Core Leadership)
Alyssa O’Grady

Alyssa O’Grady

Project Manager

Our Research Teams

Members of the CRN work diligently to advance our understanding of Parkinson’s disease. Learn more about recent CRN discoveries and achievements.

Explore the Research Community