Marissa Menard
Project Manager
Key Personnel
University of Alabama at Birmingham
Marissa graduated from the University of Vermont with degrees in Biochemistry and Molecular Genetics before moving to Birmingham and working as a researcher in the Neuroscience Molecular Detection Core specializing in histological techniques, antibody detection and microscopy.
Recent ASAP Preprints & Published Papers
Current safety recommendations for handling mouse and human αsynuclein pre-formed fibrils
α-Synuclein (α-syn) can form amyloid fibrils. Lewy bodies and Lewy neurites containing aggregated α-syn are pathological markers of Parkinson's Disease and Dementia with Lewy Bodies. To better understand the role of pathological α-syn in disease, many labs use α-syn preformed fibrils (PFFs). Neurons take up the PFFs, which act as…
α-Synuclein aggregation decreases cortico-amygdala connectivity and impairs social behavior in mice
Abnormal accumulation of insoluble α-synuclein (α-Syn) inclusions in neurons, neurites, and glial cells is the defining neuropathology of synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy. Accumulation of α-Syn inclusions in the amygdala has been well-documented in post-mortem studies of PD and DLB brains,…
