Amandine Even

Amandine Even

Neuroinflammation, Genomic Regulation, and Systemic Drivers

Amandine is a Postdoctoral fellow in the Department of Pharmacology and Physiology in University of Montréal. She obtained her thesis in immunology and more particularly in cell therapy as an innovative treatment in transplantation and in inflammatory pathologies, in Nantes (FRANCE). Now she set out to discover the role of immunity in Parkinson’s disease in the Louis-Eric TRUDEAU’s Lab.

Tags
AutoimmunityLRRK2Parkin (PARK2)PINK1T cellsVPS35

Home Team

Team Desjardins

Host Team

Team Schapira

Project Highlights

Cell-autonomous and non-cell-autonomous drivers of dopamine neuron vulnerability in Parkinson’s disease

The motor symptoms of Parkinson’s disease are linked to age-dependent degeneration of dopamine neurons. Traditionally, the loss of these neurons has been thought to stem mainly from cell-autonomous cellular dysfunctions. However, there is growing evidence suggesting it could result from complex interactions between cell-autonomous and non-cell-autonomous mechanisms. This review examines...

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