Caroline Haikal

Caroline Haikal

Alpha-Synuclein Pathology, Aggregation Kinetics, and Disease Propagation

Caroline is a postdoctoral research fellow in Dr. Michael Kaplitt’s lab at Weill Cornell Medicine. She has been utilizing AAVs to investigate factors influencing susceptibility to alpha-synuclein pathology in vivo and manipulate neuronal circuits involved in selective vulnerability. Caroline completed her PhD in Dr. Jia-Yi Li’s lab at Lund University where she studied the expression of alpha-synuclein in peripheral organs of PD patients and transgenic mouse models, as well as the cross-seeding effects between alpha-synuclein and proteins of bacterial origins. She has a multidisciplinary background with years of experience in small rodent surgery, gene therapy, complex cell and tissue culture, protein interaction assays, and advanced imaging techniques.

Tags
Alpha-synucleinCircuits and symptomsGut-brain axisMotor symptoms

Our Research Teams

Members of the CRN work diligently to advance our understanding of Parkinson’s disease. Learn more about recent CRN discoveries and achievements.