Background pattern of a brain with neural connections

Team Muqit

Mitochondrial surface as a neuroprotective signal integrator in PD

2026-Present

Human genetic discoveries suggest that defects in the clearance of damaged energy-producing centers, known as mitochondria, are linked to the onset and progression of Parkinson’s disease (PD). We aim to undertake collaborative state-of-the-art research to derive a complete picture of how PD-relevant cellular
stress is integrated at mitochondria in brain cells to orchestrate clearance of damaged mitochondria and/or mitochondrial proteins. We are a team of scientists and neurologists with a track record of working together and open science that will elaborate new mitochondrial mechanisms underlying PD, thereby generating new ideas to treat patients.

Tags
BrainCryo-ETMitochondrial dysfunctionMitochondrial morphologyPINK1ProteomicsProteostasis

Contributions

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Accolades

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In the News

Decoding the Blueprint: Advancing Personalized Parkinson’s Treatments

Decoding the Blueprint: Advancing Personalized Parkinson’s Treatments

05/21/2026 — In our community, we often hear: “If you’ve met one person with Parkinson’s, you’ve met one person with Parkinson’s.” This isn’t just an adage — it’s a biological reality. This radical variability is exactly what makes the disease so difficult to outsmart. We’ve learned that a puzzle this fragmented cannot be solved with a single, broad stroke. Our goal isn’t to find one answer for everyone, but the right answer for the right person at the right time.

Our Research Teams

Members of the CRN work diligently to advance our understanding of Parkinson’s disease. Learn more about recent CRN discoveries and achievements.