Anthony Schapira
Lead PI (Core Leadership)
University College London
Tony is Head of the Department of Clinical and Movement Neurosciences at the UCL Queen Square Institute of Neurology, and Professor of Neurology and Clinical Neurosciences. He trained in clinical and laboratory sciences in London. His group identified the mitochondrial Complex I defect in PD and the GBA enzyme deficiency in PD brain. He was elected a Fellow of the Academy of Medical Sciences in 1999 and has received numerous awards in neurology and neuroscience.
Recent ASAP Preprints & Published Papers
Introducing PIGMO, a novel PIGmented MOuse model of Parkinson’s disease
There is a pressing need for the development, characterization, and standardization of animal models of Parkinson’s disease (PD) that properly mimic the cardinal features of this disorder, comprising both the motor phenotype and neuropathological signatures. In the past few years, animal modeling has moved from neurotoxin-based approaches toward viral vectors…
Reply to: Is Gauchian genotyping of GBA1 variants reliable?
**REPLYING TO** N. Tayebi et al. *Communications Biology*[https://doi.org/10.1038/s42003-025-08059-y](https://doi.org/10.1038/s42003-025-08059-y) (2025)
