April Frazier
Project Manager
La Jolla Institute For Allergy & Immunology
April Frazier, PhD, is a Senior Project Manager in the laboratories of Drs. Cecilia Lindestam Arlehamn and Alessandro Sette at the La Jolla Institute for Immunology, La Jolla, CA. She has a science background in chemistry and cancer research, but has transitioned to project management and helps her team to investigate T cell-mediated responses against diseases and understanding healthy T cell responses.
Teams
Themes
Tags
Genetically encoded biosensors
Ex Vivo
Microscopy - optical
Acetylcholine
Mouse
Recent ASAP Preprints & Published Papers
Unaltered T cell responses to common antigens in individuals with Parkinson’s disease
Parkinson’s disease (PD) is associated with a heightened inflammatory state, including activated T cells. However, it is unclear whether these PD T cell responses are antigen specific or more indicative of generalized hyperresponsiveness. Our objective was to measure and compare antigen-specific T cell responses directed towards antigens derived from commonly…
Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures
Parkinson’s disease (PD) is a multi-stage neurodegenerative disorder with largely unknown etiology. Recent findings have identified PD-associated autoimmune features including roles for T cells. To further characterize the role of T cells in PD, we performed RNA sequencing on PBMC and peripheral CD4 and CD8 memory T cell subsets derived…
