Background pattern of a brain with neural connections

Mathieu Almeida

Co-PI (Core Leadership)

INRAE (National Research Institute for Agriculture, Food and the Environment)

Mathieu is a Research Fellow at INRAE MetaGenoPolis Institute (France). He studied bioinformatics at the Université Paris Diderot and specialized in food and digestive microbiota analysis during his phD with Dr. Pierre Renault at the INRAE Micalis Institute. He then joined Dr. Mihai Pop’s team Institute at the Center for Bioinformatics and Computational Biology, University of Maryland, College Park (USA) as a post doctoral student and developed bioinformatic metagenomic binning and assembly softwares. Before coming back to France, he joined Dr. O. Colin Stine laboratory at the University of Maryland Medical School, Baltimore (USA) where he performed epidemiological analysis on pathogens associated with diarrheal disease.

Teams

Schapira

Themes

Neuro-Immune Interactions

Recent ASAP Preprints & Published Papers

Exploring the relationship between GBA1 host genotype and gut microbiome in the GBA1L444P/WT mouse model: Implications for Parkinson disease pathogenesis

**Background** Heterozygous variants in *GBA1* are the commonest genetic risk factor for Parkinson disease (PD) but penetrance is incomplete. *GBA1* dysfunction can cause gastrointestinal disturbances and microbiome changes in preclinical models. Mounting evidence suggests that the microbiota-gut-brain axis is potentially implicated in PD pathogenesis. Whether the gut microbiome composition is influenced by host *GBA1* genetics in heterozygosis…