Background pattern of a brain with neural connections

Team Halliday

A Global Brainbank to Identify Data-Driven Molecular and Cellular Subtyping Underlying Disease Initiation and Progression in Lewy Body Diseases

2026-Present

Parkinson’s disease (PD) is different for everyone, with some experiencing early-onset, faster progression or co-pathology, like Alzheimer’s proteins. This global initiative leverages large Brain Bank cohorts to understand why and how these differences occur. We will apply artificial intelligence and advanced lab techniques to investigate how distinct brain cells and proteins contribute to the development and progression of PD. The goal is to identify specific disease subtypes, find early warning signs, and discover new treatment targets. By mapping these patterns, we hope to define biological subtypes to improve diagnosis, determine early pathologies for targeting, and identify drivers of pathological progression.

Tags
Machine learningNeurodegenerationPathologyPD progressionPD subtypesTranscriptomics

Our Research Teams

Members of the CRN work diligently to advance our understanding of Parkinson’s disease. Learn more about recent CRN discoveries and achievements.