Background pattern of a brain with neural connections
Marinka Zitnik

Marinka Zitnik

Co-PI (Core Leadership)

Collaborating PI

Harvard University

Teams

Khurana Studer

Themes

PD Functional Genomics PD Heterogeneity

Tags

iPSCs (Induced pluripotent stem cells) Alpha-synuclein Computer modeling Artificial intelligence Disease models Machine learning Seeding assays iPSC Aging iPSC neurons Environmental toxins PD heterogeneity: environment Pesticides Gene-environment interactions Exosomes

Recent ASAP Preprints & Published Papers

Contextual AI models for single-cell protein biology

Understanding protein function and developing molecular therapies require deciphering the cell types in which proteins act as well as the interactions between proteins. However, modeling protein interactions across biological contexts remains challenging for existing algorithms. Here we introduce PINNACLE, a geometric deep learning approach that generates context-aware protein representations. Leveraging…

Team Khurana

Vikram Khurana

Vikram Khurana

Lead PI (Core Leadership)
Kimberly Paul

Kimberly Paul

Co-PI (Core Leadership)
Beate Ritz

Beate Ritz

Co-PI (Core Leadership)
David Walt

David Walt

Co-PI (Core Leadership)
Marinka Zitnik

Marinka Zitnik

Co-PI (Core Leadership)
Daniel El Kodsi

Daniel El Kodsi

Project Manager, Data Manager

Team Studer

Lorenz Studer

Lorenz Studer

Lead PI (Core Leadership)
Gist Croft

Gist Croft

Co-PI (Core Leadership)
Vikram Khurana

Vikram Khurana

Co-PI (Core Leadership)
Joseph Powell

Joseph Powell

Co-PI (Core Leadership)
Johannes Jungverdorben

Johannes Jungverdorben

Project Manager

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Members of the CRN work diligently to advance our understanding of Parkinson’s disease. Learn more about recent CRN discoveries and achievements.

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