Background pattern of a brain with neural connections
Julianna Tomlinson

Julianna Tomlinson

Project Manager

Ottawa Hospital

Upon completion of her PhD in Biochemistry (uOttawa), Julianna joined Dr. Michael Schlossmacher’s team to focus on PD related topics. She has created a mouse model to study the interaction between mutant Gba1 and SNCA in vivo (manuscript is in preparation). In parallel efforts, Julianna and colleagues refined a method for the visualization of the olfactory system in mice. This publication highlights the abundance of a-synuclein within the olfactory epithelium and also showed that Snca protects mice against nasal inoculation with a neurotropic virus and lessens the bacterial load in sepsis (Tomlinson et al., JNT 2017).

Julianna has been supported as co-PI on grants from the MJFF, Weston Brain Institute and the Canadian Institute of Health Research. In her current role as Sr. Research Associate and Scientific Project Manager in the Schlossmacher team, she contributes to project conception, design and implementation, to overseeing graduate students and is leading scientific projects.

Teams

Schlossmacher

Themes

PD Functional Genomics

Tags

Inflammation Biomarkers Human Immune response

Recent ASAP Preprints & Published Papers

Elevated brain α-synuclein, phosphorylated-tau, and oxidative stress in mice that survived influenza A pneumonitis

Influenza virus infection increases the incidence of parkinsonism in humans. We have previously shown that allelic variants at the Parkinson’s disease (PD)-linked *Lrrk2* locus modulate host responses *in vivo*. Here, we asked whether Lrrk2 kinase activity alters disease outcomes in adult mice that survived a nasally acquired infection. We inoculated mice with the…

Development of a simplified smell test to identify Parkinson’s disease using multiple cohorts, machine learning and item response theory

To develop a simplified smell test for identifying patients with Parkinson’s disease (PD), we reevaluated the Sniffin’-Sticks-Identification-Test (SST-ID) and University-of-Pennsylvania-Smell-Identification-Test (UPSIT), using three case-control studies. These included 301 patients with PD or dementia with Lewy bodies (DLB), 68 subjects with multiple-system atrophy (MSA) or progressive supranuclear palsy (PSP), and 281…

Team Schlossmacher

Michael Schlossmacher

Michael Schlossmacher

Lead PI (Core Leadership)
Benjamin Arenkiel

Benjamin Arenkiel

Co-PI (Core Leadership)
Brit Mollenhauer

Brit Mollenhauer

Co-PI (Core Leadership)
Maxime Rousseaux

Maxime Rousseaux

Co-PI (Core Leadership)
Christine Stadelmann

Christine Stadelmann

Co-PI (Core Leadership)
Julianna Tomlinson

Julianna Tomlinson

Project Manager

Our Research Teams

Members of the CRN work diligently to advance our understanding of Parkinson’s disease. Learn more about recent CRN discoveries and achievements.

Explore the Research Community