Karin Reinisch
Co-PI (Core Leadership)
Yale University
Karin is David W. Professor in the Department of Cell Biology at the Yale School of Medicine. She trained as a structural biologist at Harvard, as a graduate student with William N Lipscomb and a post-doc with Stephen C. Harrison.
Recent ASAP Preprints & Published Papers
Lipid dynamics at membrane contact sites
In eukaryotes, lipid building blocks for cellular membranes are made largely in the endoplasmic reticulum and then redistributed to other organelles. Lipids are transported between organelles by vesicular trafficking or else by proteins located primarily at sites where different organelles are closely apposed. Here we discuss transport at organelle contact…
Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
Lipid transport proteins at membrane contacts, where organelles are closely apposed, are critical in redistributing lipids from the endoplasmic reticulum (ER), where they are made, to other cellular membranes. Such protein-mediated transfer is especially important for maintaining organelles disconnected from secretory pathways, like mitochondria. We identify mitoguardin-2, a mitochondrial protein…
