Background pattern of a brain with neural connections
Mercedes Prudencio

Mercedes Prudencio

Co-PI (Core Leadership)

Mayo Clinic

Mercedes is an Associate Professor (pending rank) at the University of Miami, focusing on understanding disease mechanisms to identify novel biomarkers and therapeutic targets for diseases characterized with TDP-43 pathology (TDP-43 proteinopathies). Originally from Spain, Mercedes went to the USA to study Neuroscience at the University of Florida, under the guidance of Dr. David Borchelt. After obtaining her PhD, she began her postdoctoral training with Dr. Leonard Petrucelli at the Mayo Clinic in Florida, where she established her independent research program in 2021. She recently transitioned (4/2026) as new faculty of the Biochemistry and Molecular Biology Department at the University of Miami

Teams

Themes

Tags

Single-cell multi-omics Multi-omics Alpha-synuclein Aggregation LRRK2 GBA (Glucocerebrosidase) Animal models Organoid Neurodegeneration Pathomechanism Single-cell transcriptomics Liquid-liquid phase separation PD heterogeneity: co-pathology

Recent ASAP Preprints & Published Papers

This investigator is hard at work. Articles will be shared when they are available.

Our Research Teams

Members of the CRN work diligently to advance our understanding of Parkinson’s disease. Learn more about recent CRN discoveries and achievements.