Background pattern of a brain with neural connections
Mercedes Prudencio

Mercedes Prudencio

Co-PI (Core Leadership)

University of Miami

Mercedes is an Associate Professor (pending rank) at the University of Miami, focusing on understanding disease mechanisms to identify novel biomarkers and therapeutic targets for diseases characterized with TDP-43 pathology (TDP-43 proteinopathies). Originally from Spain, Mercedes went to the USA to study Neuroscience at the University of Florida, under the guidance of Dr. David Borchelt. After obtaining her PhD, she began her postdoctoral training with Dr. Leonard Petrucelli at the Mayo Clinic in Florida, where she established her independent research program in 2021. She recently transitioned (4/2026) as new faculty of the Biochemistry and Molecular Biology Department at the University of Miami

Teams

Themes

Tags

Organoid PD heterogeneity: co-pathology Liquid-liquid phase separation Single-cell transcriptomics Pathomechanism Neurodegeneration Animal models GBA (Glucocerebrosidase) LRRK2 Aggregation Alpha-synuclein Multi-omics Single-cell multi-omics

Recent ASAP Preprints & Published Papers

This investigator is hard at work. Articles will be shared when they are available.

Our Research Teams

Members of the CRN work diligently to advance our understanding of Parkinson’s disease. Learn more about recent CRN discoveries and achievements.