Pietro De Camilli
Lead PI (Core Leadership)
Yale University
Pietro De Camilli is Professor of Neuroscience and of Cell Biology at Yale University School of Medicine and an Investigator of the Howard Hughes Medical Institute. He received an MD form the University of Milano (Italy), became interested in the cell biology of the synapse during his postdoctoral studies with Paul Greengard at Yale and was subsequently recruited by George Palade to the Yale Cell Biology faculty. He is a member of the National Academy of Science and of the National Academy of Medicine
Teams
Themes
Tags
Neural circuitry
Behavioral
Neurobehavioral
Activity Assay
Recent ASAP Preprints & Published Papers
Lipid dynamics at membrane contact sites
In eukaryotes, lipid building blocks for cellular membranes are made largely in the endoplasmic reticulum and then redistributed to other organelles. Lipids are transported between organelles by vesicular trafficking or else by proteins located primarily at sites where different organelles are closely apposed. Here we discuss transport at organelle contact…
Triglycerides are an important fuel reserve for synapse function in the brain
Proper fuelling of the brain is critical to sustain cognitive function, but the role of fatty acid (FA) combustion in this process has been elusive. Here we show that acute block of a neuron-specific triglyceride lipase, DDHD2 (a genetic driver of complex hereditary spastic paraplegia), or of the mitochondrial lipid…
