Background pattern of a brain with neural connections

Team Ulusoy

Development and Validation of Labeled Antibodies Against Mitochondrial and Oxidative Stress-Related Targets for Parkinson’s Disease Research

2026-Present

High-affinity specific antibodies targeting key cellular pathways are an essential technical tool to understand Parkinson’s disease (PD) pathophysiology. Albeit commercial antibodies exist, their specificity and reliability have not been thoroughly optimized for PD research. Furthermore, there is a demand for labeled antibodies that help visualize and quantify PD-linked markers, accelerating disease progression research and drug development. We aim to develop a versatile, multiplex-ready toolkit of knockout-validated, quality-controlled labeled antibodies, specifically optimized for applications such as flow cytometry and cyclic immunohistochemistry, allowing researchers to interrogate these targets in a cell-type and subcellular compartment–specific manner.

Tags
AntibodiesMitochondriaOxidative stress

Our Research Teams

Members of the CRN work diligently to advance our understanding of Parkinson’s disease. Learn more about recent CRN discoveries and achievements.