Geidy Serrano
Co-PI (Core Leadership)
Collaborating PI
Banner Sun Health Research Institute
Geidy Serrano is the director of the Brain and Body Donation Program Neuropathology laboratory. she works closely with multidisciplinary laboratories and investigators to support neuropathological and translational research.
Teams
Themes
Tags
Alpha-synuclein
RNA-seq
Mitochondria
PD progression
Oxidative stress
Seeding assays
Antibodies
GWAS
Conformational strains
PD heterogeneity: alpha-synuclein seeding
Recent ASAP Preprints & Published Papers
Integrating Long-Read Structural Variant Analysis with single-nucleus RNA-seq to Elucidate Gene Expression Effects in Disease
Structural variants (SVs) are a major source of genetic diversity, yet how they impact cell types in complex brain diseases remains largely unexplored, partially due to limitations of short-read sequencing. Here, we addressed this fundamental question in Parkinson's disease (PD). generating long-read whole-genome sequencing (WGS) data for 100 post-mortem brain…
Modeling cis-regulatory variation in human brain enhancers across a large Parkinson's Disease cohort
Genome-wide association studies (GWAS) have linked more than hundred non-coding genomic loci to Parkinson’s disease (PD) risk. Deciphering their functional impact on gene regulation requires cell type-aware modeling approaches to assess the effects of sequence variation on enhancer function and target gene expression. To address this challenge, we generated a…
