Jackson Schumacher
Project Manager
Massachusetts General Hospital
Jackson Schumacher is the project manager for ASAP Team Chen and a research associate at Massachusetts General Hospital and Harvard Medical School, where he works in the laboratory of Dr. Xiqun Chen. His research focuses on understanding the molecular and immune mechanisms that contribute to Parkinson’s disease, with particular interest in α-synuclein aggregation, LRRK2-associated immune responses, and neuroinflammatory pathways.
Recent ASAP Preprints & Published Papers
Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort
### Background α-Synuclein (α-syn) seed amplification assays (SAAs) have shown remarkable potential in diagnosing Parkinson's disease (PD). Using data from the Parkinson's Progression Markers Initiative (PPMI) cohort, we aimed to test whether baseline α-syn seeding activity and α-syn SAA kinetic parameters are associated with disease progression in sporadic PD, *LRRK2*-associated PD…
AutoMorphoTrack: An Automated Python Package for Organelle Morphology, Motility, and Colocalization Analysis in Live-Cell Imaging
Understanding the dynamics and interactions of intracellular organelles is critical for understanding the mechanisms of cellular homeostasis and disease. Here, we present AutoMorphoTrack, an open-source Python package for automated detection (optional thresholding), morphology classification, motility tracking, and colocalization analysis of mitochondria and lysosomes in live-cell imaging data. The package provides…
