Background pattern of a brain with neural connections
Mario Borgnia

Mario Borgnia

Co-PI (Core Leadership)

National Institutes of Health

Mario J. Borgnia is Head of the Molecular Microscopy Group and Director of the Cryo-EM Core at the National Institute of Environmental Health Sciences (NIEHS), and an adjunct professor at Duke University. He trained at Johns Hopkins University with Nobel Prize laureate Peter Agre, where he performed biophysical characterization of water transport by bacterial aquaporins. Motivated by the underlying structural mechanisms, he subsequently transitioned to cryo-electron microscopy (cryo-EM) for structural biology training at the National Cancer Institute with Sriram Subramaniam.

Teams

Themes

Tags

Fibril Alpha-synuclein Protein aggregates Pathology Proteomics Cryo-EM Seeding assays Cryo-ET Fluid-based biomarkers PD heterogeneity: alpha-synuclein seeding

Recent ASAP Preprints & Published Papers

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