YuHong Fu
Co-PI (Core Leadership)
Key Personnel
The University of Sydney
YuHong is a senior research fellow at the Brain and Mind Center of the University of Sydney, specializing in human neuropathology and the molecular mechanisms underlying neurodegenerative disease. She brings advanced histopathology expertise and extensive experience analyzing postmortem human and rodent brain tissue. Her research focuses on selective neuronal vulnerability and glial pathogenic pathways in synucleinopathies.
Teams
Themes
Tags
Non-coding RNA
in situ RNA analytics
iPSC neurons
Noradrenaline
Catecholamines
Chemogenetics
PD heterogeneity: aging
Alpha-synuclein
iPSCs (Induced pluripotent stem cells)
Recent ASAP Preprints & Published Papers
Dementia with Lewy bodies and Parkinson disease dementia - the same or different and is it important?
Biological definitions of neurological diseases are now becoming a reality, although still in the research phase. This development will recategorize neurological diseases, providing objective diagnostics and the promise of therapeutics that target biological mechanisms — similar to the strategy that has proven successful in tumours and other conditions. In this…
CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology
Mitochondrial dysfunction is a hallmark of Parkinson’s disease (PD), but the mechanisms by which it drives autosomal dominant and idiopathic forms of PD remain unclear. To investigate this, we generated and performed a comprehensive phenotypic analysis of a knock-in mouse model carrying the T61I mutation in the mitochondrial protein CHCHD2…
