Background pattern of a brain with neural connections
Matthias Mann

Matthias Mann

Lead PI (Core Leadership)

Collaborating PI

Max Planck Institute of Biochemistry

Matthias heads the Proteomics and Signal Transduction department at the Max Planck Institute of Biochemistry in Munich. As a pioneer in mass spectrometry-based proteomics, he has developed foundational technologies and computational workflows for quantitative protein analysis and biomedical applications, with emphasis on translational research including body fluid proteomics, single-cell spatial proteomics, and post-translational modifications. With nearly 1,000 publications and an h-factor of 281 (Google Scholar), he is among the most cited researchers globally. His awards include election to the National Academy of Sciences, the Heineken Prize for Biochemistry and Biophysics (shared with Ruedi Aebersold), Germany’s Leibniz Prize, and the Louis-Jeantet Prize for Medicine.

Teams

Themes

Tags

Single-cell multi-omics Multi-omics Brain Alpha-synuclein Aggregation LRRK2 GBA (Glucocerebrosidase) Animal models Proteomics Blood Artificial intelligence Organoid Seeding assays Neurodegeneration Cellular assays PD subtypes Pathomechanism Single-cell transcriptomics Disease heterogeneity Liquid-liquid phase separation PD heterogeneity: co-pathology PD heterogeneity: alpha-synuclein seeding Biomarker discovery

Recent ASAP Preprints & Published Papers

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