Team Directory

Mapping the LRRK2 signalling pathway and its interplay with other Parkinson’s disease components

Redefining PD pathophysiology mechanisms in the context of heterogeneous substantia nigra neuron subtypes

Understanding and manipulating cellular and circuit-level vulnerability to neurodegeneration in Parkinson’s disease

Circuit Mechanisms for Dopamine Neuron Vulnerability and Resilience in PD

From cancer associations to altered immunity in the pathogenesis of Parkinson’s disease

Mapping the modulatory landscape governing striatal dopamine signaling and its dysregulation in Parkinson’s disease

ASAP CRN Cloud – An ASAP Resource Team

Impaired integration of organelle function in Parkinson’s disease

The role of PD-related proteins as drivers of disease through modulation of innate and adaptive immunity

The Dual Role of Neural Activity in Parkinson’s Disease

Global Parkinson’s Genetics Program (GP2) – An ASAP Resource Team

Gut-to-brain circuit contributions to Parkinson-like phenotypes in nontransgenic rodent and primate animal models

Tracing the Origin and Progression of Parkinson’s Disease through the Neuro-Immune Interactome

Dissecting the Mechanisms Underlying Disease Progression in Parkinsonism

Mechanisms Overwhelming Protein and Organelle Quality Control in Parkinson’s Disease

Mechanisms of Mitochondrial Damage Control by PINK1 and Parkin

iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) – An ASAP Resource Team

Activation of transposable elements as a trigger of neuroinflammation in Parkinson’s disease

α-Synuclein Effects on Gut Brain Circuits and Pre-Motor Symptoms in Parkinson’s Disease

An in vivo Approach to Elucidate the Pathobiology of PD-associated Genes using Human Diseased Neurons

Co-Pathologies Drive Neuroinflammation and Progression in PD

Senescence in Parkinson’s disease and Related Disorders

Role of enteroendocrine cells in the origin of Parkinson’s pathology

The centralized microbiome analytic core (MAC) – An ASAP Resource Team

Reconstructing the Lost Nigrostriatal Circuitry in Parkinson’s Disease

Parkinson’s Progression Marker’s Initiative (PPMI) – An ASAP Resource Team

Cellular Mechanism of LRRK2 in Health and Disease

Dissecting Genetic Interactions of Parkinson’s disease associated Risk Loci

The genome-microbiome axis in the cause of Parkinson disease: Mechanistic insights and therapeutic implications from experimental models and a genetically stratified patient population.

Parkinson5D: Deconstructing Proximal Disease Mechanisms across Cells, Space, and Progression

Olfactory Circuits: Alpha-Synuclein-Rich Neurons Respond to Environmental Triggers at the Origin of Parkinson Disease

Basal Ganglia Networks in Parkinson’s Disease

Defining the Cellular and Molecular Determinants of Variable Genetic Penetrance in Parkinson’s disease

Adaptive immunity in the etiology and progression of Parkinson’s disease

Distributed circuit dysfunction underlying motor and sleep deficits in a progressive mouse model of Parkinson’s disease

Implications of Polyamine and Glucosylceramide Transport for Parkinson’s Disease (IMPACT-PD)

Activity and connectivity drive neuronal vulnerability and disease progression in Parkinson’s disease

Understanding inherited and acquired genetic variation in Parkinson’s disease through single-cell multi-omics analyses: a unique data resource

Cortical pathophysiology of Parkinsonism

Mapping the PD brain: Oligomer-driven functional genomics